CRP and necrotizing enterocolitis: Our murine model of transfusion-associated NEC resembled human NEC in its regional predilection for the ileocecal and mid-colonic segments, histopathological findings of coagulation necrosis and macrophage infiltration, circulating markers such as Cxcl2, C-reactive protein, and serum amyloid A, and the induction of inflammatory genes in affected tissues43,53.