Bioinformatic analysis indicated that upregulated CBX3/HP1γ expression predicts poor prognosis in liver cancer (Figure 1C), breast cancer (Figure 1D), pancreatic cancer (Figure 1E), and renal cancer (Figure 1F) (Kaplan-Meier plot, log-rank test, all P values< 0.001). Here, CBX3 is linked to familial pancreatic carcinoma.