GOLPH3 and neoplasm: The tumor-targeting double-cyclic ligand RGD4C (CDCRGDCFC) peptide (24, –26) was incorporated into the minor coat protein of fUSE5 and a chimera with f88.4 was constructed before introducing additional genetic sequences encoding the desired peptides in different coat protein genes by use of a subcloning strategy and site-directed mutagenesis.