Adjusted results indicated that IL-16 gene rs11556218 still showed significant association with T2DM susceptibility, and individuals carrying TG genotype and G allele showed higher risk to suffer from T2DM (OR = 1.769, 95% CI = 1.045–2.994; OR = 1.639, 95% CI = 1.087–2.471) (Table 3). The gene discussed is IL16; the disease is type 2 diabetes mellitus.