PDLIM7 and neoplasm: Nevertheless, it is known that LMP1 is involved in three classic mitogen-activated protein kinases (MAPK): ERK-MAPK, p38 MAPK and JNK/SAPK via both typical and atypical NF-kappa B pathway and PI3K pathway.20, 21, 22 Cripto-1 plays an important role in embryonic development and tumor progression as a co-receptor of TGF-β related morphological factor Nodal.23