Today, two antibodies blocking PD-1, Nivolumab (Opdivo, Bristol-Myers Squibb) and Pembrolizumab (Keytruda, MSD SHARP and DOHME GMBH) as well as one antibody targeting PD-L1, Atezolizumab (Tecentriq, Roche) [9,10], have US Food and Drug Administration (FDA) approval in NSCLC. This evidence concerns the gene CD274 and non-small cell lung carcinoma.