ABCG1 and melanoma: For example, it has been shown that mice deficient in ABCG1 and ABCA1, when fed a “western”-type diet, display reduced growth of tumors derived from subcutaneously engrafted melanoma or bladder carcinoma cells, while other studies have attempted to associate ABCA1 with epithelial mesenchymal transition in breast cancer [181,182,198,199].