In the particular context of thyroid cancer, interestingly, multiple studies [22,39,40,41,42,43], including a meta-analysis [44], have suggested the XRCC3 rs861539 variant T allele and/or, in particular, the TT homozygous genotype to be associated with increased risk of TC or, more specifically, PTC. This evidence concerns the gene XRCC3 and thyroid gland carcinoma.