TNF and neoplasm: For instance, it has been demonstrated that neutrophils can be recruited from blood to tumor microenvironments by a variety of chemokines, such as CXC ligand 8 (CXCL8) or interleukin 8 (IL-8), growth-regulated oncogene alpha (GRO-α), and CXCL1, among others, and these cells can favor the tumor progression by releasing different types of cytokines, such as tumor necrosis factor alpha (TNF-α), interleukins (ILs) -1beta (1β), 6, 15, 17, and 18 [2].