For example, data from this same survey indicate that convincing pine nut and macadamia nut allergies currently affect 0.10% (95% CI, 0.07%-0.14%) and 0.008% (95% CI, 0.004%-0.018%) of US children and adults, respectively, using identical convincing IgE-mediated symptom report criteria. The gene discussed is IGHE; the disease is allergic disease.