The association between the IFN‐γ +874T>A (rs2430561) polymorphism and the risk of chronic myeloid leukemia (CML)13 or chronic lymphocytic leukemia (CLL) was previously evaluated.14 A recent meta‐analysis suggested that the IFN‐γ +874T>A polymorphism contributes to CML and CLL susceptibility.15 Currently, studies investigating patients with AML and cytokine polymorphisms involvement are infrequent. This evidence concerns the gene IFNG and B-cell chronic lymphocytic leukemia.