We observed that the most frequent TNF-α haplotypes (rs361525, rs1800629, and rs1800750) were h5 AGGGGG haplotype (30.1% patients vs 30.3% controls) and GGGGGG (60.6% patients vs 63.5% controls), but neither was correlated with AML risk (GGGGGG haplotype P = .145, OR = 0.63, 95% CI: 0.34‐1.17; AGGGGG haplotype P = .208, OR = 0.66, 95% CI: 0.34‐1.26). The gene discussed is TNF; the disease is acute myeloid leukemia.