Moreover, in the univariate Cox regression analysis, we found that age above 65 years, TNF‐α rs1800750 variant genotype, FLT3‐ITD mutation, cytogenetic high risk, ECOG performance status ≥2, LDH level ≥600 IU/L, and PLT count lower than 40 000 cells/mm3 had an effect on OS in AML. The gene discussed is FLT3; the disease is acute myeloid leukemia.