Besides, knockdown of GLUT1 reduced glucose uptake (measured using 2-deoxyglucose) by 65% compared with scrambled control (SC), while the same cells with stably knockdown of GLUT3 and GLUT4 had no change in glucose uptake capacities (Fig. 3b) (Supplementary Fig. 2a), suggesting that GLUT1 is the primary glucose transporter in ovarian cancer cells. This evidence concerns the gene SLC2A4 and ovarian carcinoma.