The results showed that co-treatment of either the AMPK activator PF-06409577 (PF) or the TAK1 inhibitor 5Z-O could significantly inhibit tumor colony formation on the murine omenta (Fig. 7a), suggesting that the activation of AMPK or inhibition of TAK1/NF-κB signaling could be efficient for inhibiting tumor colonization in the ex vivo omental model. Here, MAP3K7 is linked to neoplasm.