The currently known shrimp immune signalling pathways vital for disease combating include Janus kinase-Signal transducer and activator of transcription (JAK-STAT) pathway, Immune deficiency (IMD) pathway, TLRs pathway, RNA interference (RNAi) pathway, c-Jun N-terminal kinase (JNK) pathway, and P38 mitogen-activated protein kinase (MAPK) pathway [4]. This evidence concerns the gene MAPK14 and Immunodeficiency.