In-depth analysis of patients having electrolyte imbalance revealed that morbidity and mortality were both increased in such cases i.e. all AKI (Acute kidney injury), MODS (Multiorgan dysfunction syndrome), CCF (Congestive cardiac failure) and SIADH (Syndrome of inappropriate secretion of ADH) cases had electrolyte imbalance. The gene discussed is AVP; the disease is acute kidney injury.