Among them, aberrant expression of SNHG14 and SNHG15 have been discovered in cancers [30, 31], expression of LINC00667 was proved as a biomarker to predict relapse free survival in patients with small hepatocellular carcinoma [32], most recently, the roles of VLDLR-AS1 and TNRC6C-AS1 in PTC have been studied [33, 34]. The gene discussed is VLDLR; the disease is cancer.