PSPH and cerebral malformation: Eleven of the 30 genes (ADAR, ANO10, C12orf4, CEP120, DLG3, DLG4, GBA2, GTPBP3, PSPH, SLC5A7, and ZC3H14) are primary ID genes annotated as not known to be associated with structural brain malformations, although when we used a different source (OMIM or Pubmed), low-penetrance structural brain anomalies were, however, reported for some of these genes (Supplementary Data 15).