Additionally, a few mutations of the aminoacyl-tRNA synthetase-interacting factor 3 (AIMP3) that affect its interaction with ataxia-telangiectasia mutated (ATM) kinases and ability to activate p53 (a tumor suppressor protein) have been reported in human chronic myeloid leukemia patients (Kim et al. 2008). Here, EEF1E1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.