Two-way ANOVA analysis indicated a general upregulation of CAT, CCS, GSTZ1, NFE2L2, SIRT1, SIRT3, SOD2, TXNIP, and VPS13C in both AD and HC LCLs due to the treatment with RV (Table 3, Figure 5b–j). The gene discussed is TXNIP; the disease is Alzheimer disease.