RARRES2 and breast cancer: In contrast to this study on a small patients ́ collective, in a metaanalysis of publicly available DNA microarray data of 3951 breast cancer patients, chemerin expression was observed to be significantly lower in breast cancer tissue than in a normal breast (p = 2.17 × 10−7) and use of Kaplan–Meier plotter software [64] revealed that high chemerin expression in breast cancer tissue did not affect overall survival (OS), but turned out to negatively affect relapse-free survival (RFS; p = 0.015; Figure 2).