The possibility of boosting UCH-L1 de novo expression in nasopharyngeal cells by the EBV oncogene LMP1 (Figure 3A), a well-established viral pro-metastatic factor in nasopharyngeal carcinomas [77,78,79], provided an ideal cellular test system for the UCH-L1 selective inhibitor LDN-57444: Both, “free” and “micellated” forms of the compound statistically reduced migration of only LMP1/UCH-L1-positive cells but not the paternal, non-invasive NP69 cells that do not express any significant levels of UCH-L1 protein (Figure 3A,C,D). Here, UCHL1 is linked to nasopharyngeal carcinoma.