KCNQ1 and atrioventricular block: miR‐1 predominantly regulates the electrical and contractile activity of the heart, by modulating atrioventricular and ventricular conduction at multiple levels.40, 41, 42 Alterations of its expression levels result in atrioventricular block, impaired contractile function and increase in ROS levels following cardiac I/R injury.9, 43, 44, 45 This microRNA targets both Cnx43 and KCNQ1,11, 13, 14, 40, 41 and, when down‐regulated, improves KCNQ1 expression in H9c2 cells,14 in line with the results achieved here.