Tumour glycolysis has been widely recognized as a central hallmark of human cancer, and emerging studies have shown that glycolysis has close relationship with cancer metastasis.12, 13, 27 To assess the effect of EZH2 on glycolysis of OSCC cells, we detected whether EZH2 could take part in glycolysis using glucose consumption and lactate production assays. Here, EZH2 is linked to cancer.