As a classical cancer signalling pathway, EZH2/STAT3 has pivotal roles in cancer growth and metastasis.14, 19, 32, 33 Western blot showed that STAT3 total expression levels remained unchanged in EZH2‐overexpressed OSCC cells, whereas pY‐STAT3 was enhanced (Figure 5B). This evidence concerns the gene EZH2 and cancer.