There was no significant difference on gender, age, body mass index, incidence of current smoker, CAD, hypertension, dyslipidemia and beta-blockers use, resting heart rate, peak heart rate, creatinine, cardiac troponin I (cTnI), N-terminal pro-brain natriuretic peptide (NT-proBNP) among the three groups. The gene discussed is NPPB; the disease is coronary artery disorder.