CDH5 and central core myopathy: Consistently, the expression levels of metastasis-related effector molecules, including VE-cadherin, VEGF-A, FGF2, and MMPs, were dramatically decreased (Figure 1D, Figure S3G and Figure S4A), whereas the metastasis suppressors, BRMS1 and TXNIP, were upregulated (Figure S4B-C) in the CCo group.