To examine whether inhibiting MCT1 impacts Taxol sensitivity of breast cancer tumors in vivo, we performed xenograft experiments by injection of MCF7 Taxol resistant cells into nude mice and began Taxol alone, Taxol plus MCT1 inhibitor or Taxol plus miR-124 mimic treatment after the tumors reached 5 mm in diameter. This evidence concerns the gene SLC16A1 and breast cancer.