GLI1 and gastric cancer: Our results indicates that Integrin αvβ3 mediates cell aggregates and maintains the viability of peritoneal MCAs in GC cells (Supplementary Fig. S1a–c).To determine whether Integrin αvβ3 regulates GLI1, Integrin αvβ3 inhibitor Cilengitide, co-stimulator ligand RGD and a blank control DMSO were added to BGC823 MCAs and SGC7901 MCAs, respectively.