MAPT and Schnyder corneal dystrophy: Hierarchical linear regression analysis showed that the number of fulfilled SCD-plus features was a significant predictor of a reduced (more pathological) CSF-Aß-42 level (ß = − .225, p < .005) (Fig. 2) and of a reduced (more pathological) CSF Aß-42/tau-ratio (ß = − .189, p < .01) independent of age, sex, and education.