IL-30 promotes PC-SLC viability, self-renewal ability, tumorigenic and metastatic potential, as revealed by using a fully immunocompetent orthotopic murine model and it regulates, essentially via STAT1 and STAT3 signaling, a range of pro-inflammatory and chemokine/chemokine-receptor genes that promote tumor growth [8]. This evidence concerns the gene IL27 and neoplasm.