IFNG and Sepsis: Studies carried out so far, using IL-30KO mice, suggest that the lack of host IL-30 increases the susceptibility to liver injury, by boosting IFNγ production by CD4+T cells [15], increases the sensitivity to LPS-induced sepsis, through the inhibition of IL-10 and up-regulation of IFNγ production by Natural Killer–like T cells [35].