IL27 and neoplasm: To assess the consequences of the lack of host- and PC-SLC- derived IL-30 in tumor progression, we next looked at the development of spontaneous metastases in both WT and IL-30KO mice, bearing IL-30-silenced or control tumors (mice were sacrificed when the primary tumors reached similar average volumes; 795 mm3, ANOVA: p = 0.775049).