BMI1 and neoplasm: Up-regulation of Bmi1 gene has been explored in several tumor types, such as nasopharyngeal carcinoma, non-small cell lung carcinoma, medulloblastoma, colon carcinoma, and metastatic melanoma (Zacharek et al., 2011; Wang et al., 2013; Ferretti et al., 2016; Zhang et al., 2016; Bakhshinyan et al., 2018).