For instance, genetic loci in BUD13, ZNF259, APOA5, LPL, and CETP in Europeans [18], TCF7L2, APOA5, LPL, CETP, APOE, and APOC1 in African Americans [19], CA10 and CTNNA3 in Africans [20], APOA1/C3/A4/A5 gene cluster region in Finnish [21], APOA5, BUD13, and ALDH2 in Han Chinese [22], LPL, MYL2, CCDC63, and CETP in Koreans [23], and APOA and COLEC12 in Taiwanese [24] have been attributed for strong association with MetS. The gene discussed is APOA5; the disease is metabolic syndrome.