ABCG2 and colorectal carcinoma: Notably, high levels of ABCG2 were found mainly in the tissue from colorectal carcinoma patients with a high resistance to 5-fluorouracil-based chemotherapy and, importantly, the same tissues revealed an increased expression of HuR but highly reduced levels of mir-519 [44], one of the well-characterized HuR suppressing miRs in colon carcinoma and other human tumor cells [46].