Some of these pathways (with adjusted p < 0.001) are the TGF-beta signaling pathway, MAPK signaling pathway, neurotrophin signaling pathway, glycosphingolipid biosynthesis lacto and neolacto series, Ras signaling pathway, arrhythmogenic right ventricular cardiomyopathy (ARVC), and hepatitis B. Although several of these pathways are not related to the CNS, we have still included them here for completeness. The gene discussed is BDNF; the disease is arrhythmogenic right ventricular cardiomyopathy.