Trock and coworkers performed an analysis of some common genetic alterations of prostate cancer (chromosome 8q gain (MYC), 8p loss, and PTEN loss) in adjacent GP3 and GP4 tumors in GS6 and GS7 tumors: 8q gain, 8p loss and PTEN loss were more common in G3 cores derived from GS7 than GS6 tumors [10]. The gene discussed is PTEN; the disease is prostate carcinoma.