Petrovics et al. compared the genomic profile of localized prostatic cancers between CaM and AAM and identified a recurrent deletion of LSAMP (Limbic System Associated Membrane Protein) gene on chromosome 3q13.31, prevalent in prostate cancers of AAM compared to CaM (26% vs. 7%); this gene deletion was associated with rapid disease progression [314]. This evidence concerns the gene LSAMP and Familial prostate cancer.