NPM1 is a ubiquitously expressed, multifunctional, nucleolar shuttle protein responsible for transporting proteins between the nucleus and the cytoplasm—it is attributed to both oncogenic and tumour-suppressive functions, with additional physiological roles in ribosome biogenesis [90,91], mRNA processing [92], chromatin remodelling [93], cell growth and proliferation, and regulating apoptosis [94]. Here, NPM1 is linked to neoplasm.