Despite enhanced eosinophilia in CD200R−/− mice, fungal burden was not significantly altered, which is in contrast to other studies where a reduction in eosinophilia (for example in surfactant protein D, Scavenger Receptor A, NADPH oxidase or eosinophil knockout mice) 25, 26 is associated with reduced fungal burden. This evidence concerns the gene SFTPD and Increased total eosinophil count.