Levels of ALT were significantly decreased in AD compared with CN (odds ratio, 0.133; 95% CI, 0.042-0.422; P = .004) (Table 1), while AST to ALT ratio values were significantly increased in AD (odds ratio, 7.932; 95% CI, 1.673-37.617; P = .03). This evidence concerns the gene GPT and Alzheimer disease.