(A) Heat map depicting degree of statistical significance for difference between each mutant and wild-type cells for the indicated assays (SP, spindle positioning; V, velocity; D, displacement per event; A, activity; NT, neck transit; L, localization; %A, percent active motors; MCD, malformations in cortical development; CMT, Charcot-Marie-Tooth disease; SMA-LED, spinal muscular atrophy with lower extremity dominance; CMD, congenital muscular dystrophy). Here, SMN1 is linked to proximal spinal muscular atrophy.