The author had already proven the efficacy of the topical phytotherapeutic treatment protocol by exhibiting 42 pairs of knee-joints of 21 patients before and after the treatment irrespective of age and sex and even after failed total knee surgery where all the patients were suffering from MD confirmed with their serum test of CK-MM and aldo A (36-38, 49, 53-55) . Here, CKM is linked to Menkes disease.