APP and early-onset autosomal dominant Alzheimer disease: From “GO” analysis, these genes are implicated in general cellular functions, such as basal transcriptional machinery binding, RNA polymerase II core binding, and several transmembrane transporter activities (Supplementary Table S3) The expression of genes associated with Alzheimer’s disease such as APOE, PSEN1, PSEN2, PICALM, and APP were expressed in both groups (Supplementary Table S4).