TNFAIP6 and acute respiratory distress syndrome: Here, utilizing the murine model of PMN-dependent ALI induced by LPS (22, 23), we observed (i) the temporal transition of AMФs to an antiinflammatory phenotype coupled with generation of the cytokines IL-4 and TSG6, (ii) increases in AMФs expressing antiinflammatory markers indicative of phenotype shift in AMФs, and (iii) enhanced expression of the efferocytotic ligand Gas6 inducing the activation of efferocytosis machinery in AMФs.