PLCG1 and breast carcinoma: Kaplan-Meier and multivariate analyses of PLCγ1 transcript expression in tumours from the 1,881-sample breast cancer dataset (GOBO; Gene expression-based Outcome for Breast cancer Online; http://co.bmc.lu.se/gobo) [16], which further confirmed the negative prognostic value of high PLCγ1 protein expression in lymph-node-negative Luminal-A tumours (n = 184) (P < 0.005, P = 0.004, respectively) (Additional file 2: Figure S5).