Therefore, we generated miR-137 transgenic mice (miR-137 Tg mice) in which miR-137 is expressed in the whole brain regions with the neuron-specific Thy-1 promoter [22], and examined the effects of overexpressed miR-137 on psychiatry-like phenotypes, especially schizophrenia related-phenotypes, such as positive and negative symptom-like behavior and cognitive deficits. Here, THY1 is linked to schizophrenia.