FGF and VEGF are probably the only growth factors that directly promote the proliferation of endothelial cells.31FGFs constitutively cooperate in VEGF-induced angiogenesis and they are responsible for the development of resistance to VEGF-based antiangiogenic treatments.32, 33Accordingly, FGF inhibition may constitute an interesting new therapeutic approach to treat diseases caused by excess, uncontrolled angiogenesis.34Angiogenesis induced by FGFs leads to the formation of quite tortuous blood vessels similar to those observed in tumor angiogenesis, which are, further, quite permeable.17, 29. Here, VEGFA is linked to neoplasm.