AKT1 and cancer: We also determined the effect of Akt activity suppression by MK-2206, a drug used in clinical trials for cancer, analyzed a small population of human PCa samples for the level of activating Akt phosphorylation in the advanced stage PCa compared to early stage and BPH tissues, and highlighted the correlation between Akt1 mRNA or protein expression/activity and EMT in the advanced PCa based on few selected CBioportal studies.