AKT1 and cancer: Interestingly, our most recent study has indicated the important role of several microRNAs in the dual, stage-specific role of Akt1 in cancer with Akt1 activity suppression in the early and advanced stages of murine neuroendocrine model of PCa in a Transgenic adenocarcinoma of the mouse prostate (TRAMP) tissues resulting in entirely different set of microRNA expression [18].