AKT1 and prostate adenocarcinoma: In the current study, we performed a genomic and proteomic database analysis (http://www.cbioportal.org) [20, 21] of Akt pathway from human PCa patient studies performed in various types such as the human prostate adenocarcinomas [22-24], castration-resistant PCa [25], neuroendocrine PCa [26] and metastatic PCa [25, 27], and determined the alterations in mRNA, protein expression, and genetic mutations.