Based on these facts, in this study, it was in our interest to investigate the effect of low dose of AG (1 nM) on cell death and proliferation of human chemosensitive ovarian cancer cell lines (A2780) in the presence or absence of cisplatin (Cis), a common chemotherapeutic agent, with the emphasis on its effect to PI3K/Akt/mTOR signaling axis. Here, AKT1 is linked to ovarian cancer.