As initial IL-33 levels were also higher in the ARDS group compared to the non-ARDS group, we subdivided our patients according to the parameters “presence of PLI” and “development of ARDS,” revealing a significant difference in initial IL-33 levels between the “+PLI−ARDS” group and the “+PLI+ARDS” group. The gene discussed is IL33; the disease is acute respiratory distress syndrome.