PIM1 and hepatocellular carcinoma: Physcion-8-O-b-glucopyranoside (PG) significantlyrepressing expression of Pim-1 and changed the expression of Bcl-2and Bcl-xL, suggesting that PG induced apoptosis in HCC cells byregulating the expression of Pim-1 and consequently modulating theeffector molecules that are substrates of PIM [37,48].