Previously, we reported that Aurora‐A regulated FOXM1 at transcription level via kinase‐independent manner was essential for breast cancer stem cell.17 To test whether the kinase activity of Aurora‐A is essential for the degradation of the FOXM1 protein in TNBC, we inhibited the kinase activity of Aurora‐A by treating MDA‐MB‐231 and MCF‐7 cells with Aurora‐A inhibitor VX680. The gene discussed is FOXM1; the disease is breast cancer.