Mechanisms through which androgenic signalling could increase autism likelihood, which may have been missed in this analysis, include additional androgens or other agonists of the androgen receptor (e.g. neurosteroids like dehydroepiandrosterone [67]), interaction effects between androgens and oestrogens (e.g. coactivation of the androgen receptor by oestradiol [68]), as well as non-linear associations of androgens to autism likelihood. This evidence concerns the gene AR and autism.