MicroRNAs miR-155, miR-106b and miR-93 are reported to be overexpressed and are known to target many GBM-downregulated proteins/genes present in the network such as PC4 and SFRS1-interacting protein isoform 2 (PSIP1), nucleolar and coiled-body phosphoprotein 1 isoform 2 (NOLC1), methyl-CpG-binding protein 2 isoform 2 (MECP2), double-stranded RNA-specific adenosine deaminase isoform d (ADAR), transcriptional activator protein Pur-alpha (PURA), ELAV-like protein 2 isoform A (ELAVL2). The gene discussed is NOLC1; the disease is glioblastoma.